There is a substantial body of scientific literature demonstrating the efficacy of medication-assisted treatment (MAT) as an HIV prevention tool for people who inject drugs (PWID) (Needle and Zhao, 2010; Larney, 2010; Degenhardt et al., 2010; CDC, 2002; Metzger et al., 2011; Mathers et al., 2009). Georgia has undertaken a formal program to provide MAT to this key population since 2005. Despite progress in enrolling PWID, there is a need to maximize resources to increase the number of PWID enrolled in the program. The results generated from this study will be useful to better understand the costs of offering MAT services in Georgia.